29 Purification Jobs

Role & responsibilities : Chemical Researcher & Development Udyog Vihar, Ecotech-II, Udyog Vihar, Greater Noida, Uttar Pradesh 201306, India Full-time Company Description At TAPI, were not just a companywere a community committed to advancing health from the core. As the world’s leading supplier of active pharmaceutical ingredients (APIs), we partner with 80% of the top 50 global pharmaceutical companies. With a legacy spanning over 80 years and a portfolio of more than 350 products, as well as custom CDMO services, we’re shaping the future of health worldwide. Our strength lies in our people—a team of over 4,200 professionals across 13 state-of-the-art facilities in Italy, Hungary, the Czech Republic, Croatia, Israel, Mexico, and India. Together, we innovate, solve problems, and deliver excellence. Join us and be part of a mission that transforms lives. Job Description Are you a passionate scientist with a strong background in organic chemistry. process development? Join our innovative team at our state-of-the art Global R&D Centre , where your expertise will contribute to the development of life-changing therapies. Key Responsibilities – What You’ll Be Doing: Literature & Patent Research Diving deep into scientific literature and patents—gathering insights on specific molecules or synthetic steps to support Lead Selection and Route Scouting (LSR) . Synthesis & Characterization Using both Solid and Liquid Phase Synthesis (SPPS) techniques, develop and synthesize . Then characterizing them using LC-MS , NMR , and HPLC to ensure purity and sequence accuracy. Analytical Techniques & Quality Control From MALDI-TOF to spectroscopy , a range of analytical tools to identify compounds and maintain strict quality control and to make sure it’s all documented with precision. Strategic Chemistry Designing and executing synthetic strategies for complex molecules is both a challenge and a passion. It involves a deep understanding of protecting groups , coupling agents , and the core principles of chemistry. Compliance & Clean Lab Practices To follow GLP and GMP standards to the letter, ensuring a clean, safe, and organized lab environment that supports high-quality research. Technical Competencies: Focus on synthesis , literature search , developing and analyzing , and its characterization . Must have handled Synthesizers (Manual/Automatic), Purification Using Preparative HPLC, Lyophilizer and must be aware about Membrane filtration process. Broader scope including technology development , cross-functional collaboration , and process optimization . Qualifications We’re looking for candidates with a strong academic background and hands-on industry experience in organic chemistry and process development. The ideal candidate will have: M.Sc. in Organic Chemistry with a minimum of 3-5 years of relevant industrial experience OR Ph.D. in Chemistry with at least 1-2 years of experience in process development and scale-up. In addition to academic credentials, we value: Sound knowledge of organic chemistry, Spectroscopy, Drug Regulatory Affairs & Quality Assurance ICH Guidelines and IP understanding Good experimental hand & Scale-up knowledge Innovative thinking & excellent observance Problem Solving Ability Excellent teamwork and collaboration within & with other functions Effective communication & Presentation skills Planning & Organization Additional Information Make Your Mark with TAPI Your journey with TAPI is more than a job—it’s an opportunity to make a lasting impact on global health. If you’re ready to lead, innovate, and inspire, we’re excited to welcome you to our team. Together, let’s shape the future of pharmaceuticals. Apply on top of this page and our talent acquisition team will be in touch soon! "API experience is required" Interested candidate can connect on 8076954558 or else share your profile on *jasleen.kaur@tapi.com*

Job Summary: The R&D Chemist is responsible for conducting research, developing new chemical products, and improving existing formulations. This role involves working in a laboratory setting, performing experiments, analyzing data, and ensuring that products meet the required quality, safety, and performance standards. The R&D Chemist will collaborate with cross-functional teams to drive innovation and support the companys product development initiatives. Key Responsibilities: Research & Development: Conduct experiments to develop new chemical products or improve existing formulations. Perform research on the properties, composition, and reactions of substances to develop new processes or materials. Develop formulations for chemical products, ensuring that they meet performance, quality, and safety standards. Innovate new product ideas and applications based on market trends, customer needs, and emerging technologies. Analyze experimental data, interpret results, and make recommendations for further research or product optimization. Laboratory Work: Perform laboratory experiments using chemical techniques, including synthesis, purification, and characterization of chemical compounds. Maintain accurate records of experimental procedures, results, and observations in laboratory notebooks. Operate and maintain laboratory equipment, ensuring accurate and reliable results. Ensure that all laboratory work complies with safety regulations and standard operating procedures (SOPs). Product Testing & Analysis: Conduct tests to evaluate the performance, stability, and safety of chemical products. Use analytical techniques such as chromatography, spectroscopy, and titration to measure the chemical properties of substances. Interpret test results and adjust formulations to optimize product performance or resolve issues. Work closely with quality control and production teams to ensure that products meet required standards before commercialization. Collaboration & Cross-functional Support: Collaborate with the production, quality assurance, and regulatory teams to ensure that new formulations are scalable for manufacturing. Support the technical sales team by providing expertise on the chemical properties and applications of products. Liaise with suppliers and external research institutions to source materials or gather information for product development. Documentation & Reporting: Prepare detailed reports on research findings, product development progress, and experimental results. Document all research and development activities, ensuring that accurate records are maintained for regulatory and patent purposes. Present research findings and new product ideas to senior management and other departments. Assist in preparing technical documentation for new product launches or regulatory submissions. Regulatory Compliance & Safety: Ensure that all R&D activities comply with relevant regulatory standards and industry guidelines. Follow proper safety protocols in the laboratory, ensuring safe handling, storage, and disposal of chemicals. Stay up-to-date with changes in chemical regulations and industry trends to ensure that products are compliant. Continuous Improvement & Innovation: Stay informed about advancements in chemical research, materials science, and industry technologies. Participate in training and development programs to enhance knowledge of new methods, tools, and techniques. Propose new ideas and improvements for products, processes, and materials to keep the company at the forefront of innovation. Qualifications: Bachelors degree in Chemistry, Chemical Engineering, or a related field. 3+ years of experience in an R&D or laboratory environment, preferably in the chemical, pharmaceutical, or materials industries. Strong knowledge of chemical synthesis, formulations, and analytical methods. Experience with laboratory techniques such as chromatography, spectroscopy, and titration. Excellent problem-solving skills and attention to detail. Proficiency in using laboratory equipment and software for data analysis. Ability to work independently and as part of a team in a dynamic, fast-paced environment. Preferred Qualifications: Masters degree or PhD in Chemistry or related discipline. Experience in product development in industries such as coatings, adhesives, polymers, or specialty chemicals. Familiarity with regulatory standards (e.g., REACH, OSHA, GHS) and industry-specific guidelines. Knowledge of Good Laboratory Practices (GLP) and ISO standards. Strong project management and communication skills.

Job Overview The Senior Principal Scientist in Peptides Purification will lead, design, and execute advanced research projects focused on the purification of peptide molecules Key Stakeholders: Internal Operations, Marketing, Quality, Finance, Sr. leaders Key Stakeholders: External Vendors and Customers on need basis Reporting Structure Functional reporting to Associate Director R&D Experience Minimum 10+ years of hands-on experience in peptide purification Competencies Leadership skills Ability to connect the dots in various situations, seeing the risk and keep the mitigation plans. Clear communication. Analytical mindset. Quick and effective decision making. Stakeholder management Roles and Responsibilities: Lead and manage peptide R&D Purification projects from inception to completion, ensuring timelines, budgets, and quality standards are met. Design and implement advanced purification strategies for peptide molecules Develop and implement strategic plans for peptide research and development in alignment with organizational goals and objectives. Purification of Peptide impurities by using solution & solid phase technique. Create the Innovative Research and Development Environment Train and guide the research teams to improve on developing/ adopting new chemical technologies. Drive positive & major EHS Cultural transformation Initiatives Take ownership of solvent recovery and yields improvement. Mentor and manage a team of scientists and research associates working in peptide purification. Ensure compliance with regulatory guidelines and requirements governing peptide drug development and help the teams in successful regulatory inspection with no critical observations. Qualifications Ph.D. in Biochemistry, Organic Chemistry, Chemical Engineering, or related field with a focus on peptides.

Role & responsibilities Strategizing the Biosimilar process development based on CHO & other mammalian cells lines for developing non-infringing Upstream process. Understanding the cell Lines, cell culture & Bioreactor process based biotherapeutic proteins development towards submission in India & various regulated countries. Good knowledge of Cell line development & cell line characterization. Understanding developmental requirements for India, ROW & regulated market (Phase-I & III) and their fulfilment during development of respective geographies. Planning and execution of experiments as part of process development, Upstream activities at shake flask and Bioreactor stages for recombinant molecules. Responsible for Media & Feed formulation & preparation, components role verification & utilization based on spent media analysis for overall process improvement Designing and conducting the process characterization for upstream development Responsible for Process scale up & scale down operation at various scales of Bioreactors. Responsible for analysing scientific research data using statistical software to analyse trends and patterns to help interpretation & establish the robust process. Capable of leading a team of Scientist & Sr. Scientist for day-to-day Cell culture works at lab and active, productive coordination with cell culture and analytical groups for timely completion of project. Oversee and coordinate work performance at Production plant or any 3rd party Manufacturing unit Support to commercialization activities (assistance for tech transfer, process validation studies, manufacturing investigation, trend evaluation & troubleshooting) Literature survey, Patents identification & writing research papers Preparing CMC data package, URS, Qualifications, Process development report, BMR & implementation of Quality system. Engaging himself / herself in frequent scientific discussions, constant learner & responsible for targeted deliverables. Preferred candidate profile Candidate should be well versed with latest developments in Upstream related Instruments, Cell culture & Bioreactor process for implementing techniques towards developing the robust process in time bound manner. The candidate should be a very good team player and comfortably connect inter & intra departmental teammates with an expedited productive outcome. Need to demonstrate and continue implementing good documentation practices with data traceability. Should inculcate a scientific acumen in team members and exhibit a good leadership. A clear and convincing oral and written communication in English is desired. He / She should have the good working knowledge of MS office, handling statistical software and related analytical tools. Principal Scientist, preferably PhD /post docs from abroad having Bioprocess cell culture experience.

We have requirement for R&D Peptide Downstream Purification. We are looking for 3 to 6 Years of Experience in Downstream purification. Having CDMO Division exp, is added advantage. Work Location: CRAMSN Research Park , Pashmylaram, Patancheru, Hyderabad.

As a Peptides Production Executive, you will be responsible for learning and assisting in the production of peptides according to established protocols and quality standards. This position is designed to provide hands-on training in peptide synthesis, purification, and related processes. Key Responsibilities: Understand and follow standard operating procedures (SOPs) for peptide synthesis. Assist in the preparation of reagents, solutions, and equipment for peptide production. Execute peptide synthesis under the guidance of experienced personnel Learn and perform purification techniques such as HPLC, chromatography, and filtration. Assist in maintaining accurate records of production and testing activities. Follow Good Manufacturing Practices (GMP) and safety guidelines. Learn to operate and maintain peptide production equipment. Report equipment malfunctions or abnormalities promptly. Maintain accurate and detailed records of all production activities. Compile data and assist in preparing production reports. Communicate effectively with team members and supervisors. Contribute to the identification and implementation of process improvements. Provide feedback on procedures to enhance efficiency and quality Attend training sessions to enhance knowledge and skills. Actively participate in professional development opportunities. Experience Min 1 Year experience in Peptides manufacturing Competencies Basic understanding of peptide synthesis principles is a plus. Strong attention to detail and commitment to quality. Ability to work in a team-oriented environment. Good communication and interpersonal skills. Willingness to learn and adapt to new processes. Responsibilities Qualifications Masters/Bachelors degree in Chemistry or a related field.

Job Description Job Overview As a Peptides Production Executive, you will be responsible for learning and assisting in the production of peptides according to established protocols and quality standards. This position is designed to provide hands-on training in peptide synthesis, purification, and related processes. Key Responsibilities: Understand and follow standard operating procedures (SOPs) for peptide synthesis. Assist in the preparation of reagents, solutions, and equipment for peptide production. Execute peptide synthesis under the guidance of experienced personnel Learn and perform purification techniques such as HPLC, chromatography, and filtration. Assist in maintaining accurate records of production and testing activities. Follow Good Manufacturing Practices (GMP) and safety guidelines. Learn to operate and maintain peptide production equipment. Report equipment malfunctions or abnormalities promptly. Maintain accurate and detailed records of all production activities. Compile data and assist in preparing production reports. Communicate effectively with team members and supervisors. Contribute to the identification and implementation of process improvements. Provide feedback on procedures to enhance efficiency and quality Attend training sessions to enhance knowledge and skills. Actively participate in professional development opportunities. Experience: Min 2 to 3 Yrs experience in Peptides production department. Preferred candidate profile: Basic understanding of peptide synthesis principles is a plus. Strong attention to detail and commitment to quality. Ability to work in a team-oriented environment. Good communication and interpersonal skills. Willingness to learn and adapt to new processes. Responsibilities Qualifications Masters/Bachelors degree in Chemistry or a related field.

Department: R&D Biotech (Downstream Process) at Airoli, Navi Mumbai Role: Downstream Process & Formulation development Opportunity: This role provides an opportunity to learn and grow to an advance level of expert in the field of downstream processing & formulation development of Recombinant Biotherapeutics Proteins. Role & responsibilities Development of non-infringing downstream purification process for cell culture based biotherapeutic proteins towards submission in India & various regulated countries. Understanding developmental requirements for India, ROW & regulated market (Phase-I & III) and their fulfilment during development of respective geographies. Responsible for end-to-end process optimization of all purification unit operations viz. chromatography (Affinity, IEX, HIC, etc.), UF/DF TFF, Nanofiltration, etc. towards optimization of overall DSP process. Should carry out troubleshooting in least possible time. Fine execution of day-to-day purification works at lab and active, productive coordination with cell culture and analytical groups for timely completion of project. Responsible for Scale up and technology transfer along with manufacturing support during troubleshooting at mfg. site. If required, ensuring the physical presence at manufacturing site during critical scale up/GMP batches like clinical batch, engineering batch, PV batches, etc. Regular biweekly updates to vertical heads with conclusion of performed experiments and way ahead. Align the overall development work, experiments with project deliverable timelines and company goals. Empower the team with frequent scientific discussions and energizing them for more productive outcome. Preferred candidates Candidate should be a good team player and comfortably connect inter & intra departmental teammates with expedited productive outcome. Need to demonstrate and continue implementing good documentation practices with data traceability. Should inculcate a scientific acumen in team members and exhibit a good leadership. Strong communication Candidate should be well versed with latest developments in purification techniques and look forward for implementing them in process. Should be expert in handling and troubleshooting of DSP related instruments including purification systems, TFF systems, Nanofiltration, etc.

Job Summary Person at this position takes ownership of a module and associated quality and delivery. Person at this position provides instructions, guidance and advice to team members to ensure quality and on time delivery. Person at this position is expected to be able to instruct and review the quality of work done by technical staff. Person at this position should be able to identify key issues and challenges by themselves, prioritize the tasks and deliver results with minimal direction and supervision. Person at this position has the ability to investigate the root cause of the problem and come up alternatives/ solutions based on sound technical foundation gained through in-depth knowledge of technology, standards, tools and processes. Person has the ability to organize and draw connections among ideas and distinguish between those which are implementable. Person demonstrates a degree of flexibility in resolving problems/ issues that atleast to in-depth command of all techniques, processes, tools and standards within the relevant field of specialisation. Roles & Responsibilities Responsible for requirement analysis and feasibility study including system level work estimation while considering risk identification and mitigation. Responsible for design, coding, testing, bug fixing, documentation and technical support in the assigned area. Responsible for on time delivery while adhering to quality and productivity goals. Responsible for traceability of the requirements from design to delivery Code optimization and coverage. Responsible for conducting reviews, identifying risks and ownership of quality of deliverables. Responsible for identifying training needs of the team. Expected to enhance technical capabilities by attending trainings, self-study and periodic technical assessments. Expected to participate in technical initiatives related to project and organization and deliver training as per plan and quality. Expected to be a technical mentor for junior members. Person may be given additional responsibility of managing people based on discretion of Project Manager. Education and Experience Required Engineering graduate, MCA, etc Experience: 5-8 years Competencies Description Protocol Stack/Call Processing- RAN/CN engineer is one who has done one or more of the following with respect to Protocol Stack/CallP/Applications of different Radio Access Network or Core network technologies (2G/3G/4G/5G) - Design Bug Fixing/Sustenance Porting on top of Different Platforms Platforms- Mandatory to have worked on one or more of the following: Carrier Grade Middleware (User Level) Linux / CG Linux, VxWorks Technology Standard- Mandatory to have worked on one or more of the folowing: 2G/3G/4G/5G RAN or CN protocols as per 3GPP/ETSI standards, working on protocol/Call processing/OAM modules. Worked on layers from L2 and above. Tools- Mandatory to have worked on one or more of the following: GDB ClearCase Wireshark Klocworks/Purify Languages- Mandatory to have worked on one or more of the following: C/C++ Scripting(bash/perl/python/expect) Specialization-2G, 3G, 4G, 5G, VSAT-SATCOM

- Conduct the experiment as per planning - Calculate reagent quantities, yields, etc. - Enter the experimental observations in Electronic Lab Notebook (ELN) - Conduct chemical reactions in batch and photochemical reactors - Handle the chemistries such as photochemistry, alkylation, oxidation, nitration, diazotization, chlorination, fluorination, vapourphase chemistry, etc - Conduct various purification techiques like fractional distillations, column chromatography and extractions - Prepare reports and documents as per product development element review methodology - Maintain the inventory of the reactors as per the laboratory management element - Interpret the GC, HPLC and wet chemistry results

Job Description Jubilant Bhartia Group Jubilant Bhartia Group is a global conglomerate founded by Mr Shyam S Bhartia and Mr Hari S Bhartia with strong presence in diverse sectors like Pharmaceuticals, Contract Research and Development Services, Proprietary Novel Drugs, Life Science Ingredients, Agri Products, Performance Polymers, Food Service (QSR), Food, Auto, Consulting in Aerospace and Oilfield Services Jubilant Bhartia Group has four flagships CompaniesJubilant Pharmova Limited, Jubilant Ingrevia Limited, Jubilant FoodWorks Limited and Jubilant Industries Limited Currently the group has a global workforce of around 43,000 employees, About Jubilant Biosys Jubilant Biosys Ltd is a part of the Jubilant Pharmova family of companies with R&D centres in India and business offices in Asia and North America With our global reach, Jubilant Biosys provides comprehensive drug discovery services and contract research servicesfrom target discovery to candidate selection and with flexible business models (FFS, FTE and risk shared)in partnership with leading worldwide healthcare companies, With a clear scientific focus in oncology, metabolic disorders, central nervous system (CNS) diseases, pain and inflammation, Jubilant Biosys has rapidly emerged as a leading collaborator for pharmaceutical and biotechnology companies worldwide In each of these therapeutic areas, Jubilant Biosys has developed a deep level of expertise in discovery informatics, computational chemistry , medicinal chemistry, structural biology , biology,in-vivo,in-vitromodels and translational sciences Combined with strong clinical development and manufacturing capabilities from other Jubilant subsidiaries, Jubilant Biosys has risen as a fully integrated contract research organization in India and headquartered at Bengaluru with end-to-end solutions, Our ability to be the preferred collaborator in the drug discovery domain is sustained by our commitment to comply with and continually improve our quality systems and to provide the following services: Contract Research Preclinical CRO Drug Discovery Virtual Screening Protein Crystallization Toxicology &In-vitroADME Medicinal Chemistry Synthetic & Developmental Chemistry Pharmacology Jubilant Biosys collaborates with the worlds leading pharmaceutical, biotech companies, academic institutions and research foundations, Find out more about us at jubilantbiosys, The Position Organization : Jubilant Biosys Designation & Level: RA / SRA (S1/S2/S3/S4) Location: Greater Noida Department: Analytical Key Responsibilities Having exposure of 1-8y in analytical chemistry (HPLC/LCMS/NMR or purification) Interaction with synthetic team and problem solving skills, Should be able to handle the respective instrument Knowledge of instrumental technique with its application Should be able to handle routine analysis independently on respective instrument, Experience in method development on HPLC/LCMS will be desirable but not necessary Maintenance, cleaning, documentation and calibration of analytical instruments, Maintain laboratory as safe working place, Person Profile Qualification: - Sc (Analytical Chemistry) Experience: - 2 years of relevant experience Jubilant is an equal opportunity employer All qualified applicants will receive consideration for employment without regard to age, ancestry, citizenship, colour, gender identity or expression, genetic information, marital status, medical condition, national origin, political affiliation, race, ethnicity, religion or any other characteristic protected by applicable local laws, regulations and ordinances,

We are seeking experienced chemists to join a talented and highly motivated team, involved in the purification of organic compound. The responsibilities will include pursuing a diverse R & D Program. Candidates should have an M. Sc. Degree in Organic Chemistry and have some working experience in HPLC and spectrophotometer.

Role and Responsibilities Do literature search for a given step(s) / molecules and support in LSR Organize for relevant patents and papers from literature Developing, synthesizing, and analyzing peptides using various techniques like Solid & Liquid Phase Peptide Synthesis (SPPS), LC-MS, and NMR Researcher will be responsible for characterizing peptides, ensuring quality control, and contributing to research projects by designing experiments and analyzing data Developing and executing synthetic strategies for complex molecules. Purifying and analyzing synthesized peptides to assess sequence and purity. Understanding and applying principles of peptide chemistry, including the use of protecting groups and coupling agents Acquiring and interpreting data from analytical techniques like HPLC, LC-MS, and MALDI-TOF. Using spectroscopic techniques to analyze and identify compounds. Maintaining accurate records and reports of analytical data Adhering to Good Laboratory Practices (GLP) and Good Manufacturing Practices (GMP). Maintaining a clean and organized laboratory environment. Competencies required Sound knowledge of Organic Chemistry & Spectroscopy ICH Guidelines and basic IP understanding Good experimental hand & Scale-up knowledge Critical Thinking & excellent observance Problem Solving Ability Excellent teamwork and collaboration within & with other functions Good communication Qualifications, Education and skill Requirements M.Sc. Organic Chemistry with 3-5 years industrial experience Ph.D. Chemistry with 12-year Industrial experience Interested candidate can share their profile on jasleen.kaur@tapi.com or connect on 8076954558.

Role & responsibilities Expertise in carrying out Multi-step synthesis of organic molecules from milligram to multi-gram scales and their characterization. Responsible for the development efficient synthetic process, which leads to better yields and quality of the product, with less cycle time and cost. Capturing proper learning of the project & would be responsible for maintaining the confidentiality of the project as per the IPR guidelines. Scaling up of process and technology transfer from lab to plant and trouble shooting at the time of scale up. Interpretation of analytical reports like HPLC, GC, NMR, LCMS, IR, GCMS. Knowledge of designing route of synthesis for target molecule. Carried out experiments in laboratory and optimize process in terms of Regulatory Affairs (RA), Safety, cost and time effectiveness. Strong knowledge on process validation in laboratory and demonstration in plants. Adept at preparing documents like Technology transfer document (TTD), Process development report (PDR), presentations and reports for review meetings. Process validation and optimization with QBD. Preparing documents like Solubility chart, Material balance, Green card, Hold time study, Details of process, MSD. Literature search .through Sci-finder and Reaxys Ability to handle linear and parallel multi-step organic synthesis Experienced with purification techniques like thin layer & column chromatography, Crystallization and distillations. Structural elucidation through NMR (1H, 13C), IR, Mass (LC/MS, GC/MS). Good Co ordination with Cross functional teams as well as team mates. Accurate record keeping in laboratory notebook (LNB) and (ELN).

Alembic pharmaceutical is looking for suitable professional for the position of Executive / Senior Executive - Peptide Production for our API site based near Vadodara. Job Criteria : B.Tech / M.sc Minimum 1 to 6 years of relevant experience working on peptide production. Good communication skills. Role & responsibilities Handling of peptide products, and knowledge on handling peptide products in GMP environment. Handling of Peptide Synthesis, both solid phase and solution phase. Handling of RP-HPLC Column 50 mmid, 110 mmid, 200 mmid, 300 mmid, 450 mmid , 800 mmid. Handling of Ion exchange chromatography. Handling of lyophilizer, Nano filtration system, TFF system. Handling of long chain to short chain peptides. Prepare the area/section for batch production as per QA guidelines. Supervise equipment operation in assigned production area and maintain critical process parameters as mentioned in Batch Manufacturing Record (BMR). Ensure personal protective equipment are worn by all employees and safety parameters are observed by plant operators and discipline is maintained. Coordinate with service departments for meeting the requirement(s) of the plant. Intimate Quality Control department for in process analysis as per production plan. Perks and benefits Best in Industry

Role & responsibilities 1. Candidate should be B-tech (chemical) preferably. 2. Candidate should have minimum 3 to 10 years work experience in Peptide R & D, PD, MS & T, Tech transfer. 3. Candidate should have work experience on peptide SPPS/LPPS upstream (Synthesis) and Downstream (Purification) process. 4. Candidate should have hands on SPPS peptide synthesizer, Preparative HPLC, Column packing/ unpacking, HETP, Lyophilizer etc. 5. Candidate should have involves with R & D team for what if studies / to identify process requirements and to ensure the process can be execute smoothly at manufacturing scale. 6. Candidate should enough competent for technology adsorption, scale up and validation support for the peptide API. 7. Candidate should have able to Monitoring peptide upstream and downstream process and ability to demonstrate to operators. 8. Candidate is responsible Ensure we make scalable, robust and competitive peptide APIs. 9. Support the CFTs with continuous process and projects improvement, implementation of new technologies and products, scale-up and troubleshooting. 10. Responsible to prepare/review technical documents and other allied activities. 11. Train and support team adequately to accomplish the day to day tasks. 12. Ensure self and team members safety at all time. Coordinate with CFTs to meet the same. 13. Any other relevant activities assigned by reporting manager to be taken up on priority basis. 14. Operation of softwares like SAP, LIMS, WMS, GxP Digitize and Documentum as per applicability

Execute process development activities for pharmaceutical products at laboratory scale Design and implement experiments to optimize manufacturing processes for increased efficiency and product quality Conduct and analyze data from characterization and optimization studies Prepare the documents like PIS, sampling plan and risk matrix for pilot scale batches (Confirmatory batch and exhibit batch manufacturing) Troubleshoot process issues and implement corrective actions Collaborate with cross-functional teams including manufacturing, quality assurance, and regulatory affairs Author and review technical reports, batch records, and standard operating procedures Ensure compliance with cGMP regulations and company policies Participate in technology transfer activities to support scale-up and exhibit batches. Stay current with industry trends and emerging technologies in pharmaceutical process development Present findings and recommendations to group leader. Contribute to continuous improvement initiatives within the department Qualification M. Pharmacy Additional Information

Responsibilities: * Monitor equipment performance and report issues promptly * Maintain plant cleanliness and safety standards * Follow safety procedures at all times * Operate hydrogen purification system using ITI skills Annual bonus Provident fund

Core Purpose of the Role: Personnel handling this profile will be responsible for conducting reactions and delivering final compounds within a fast turnaround time, meeting the specific requirements of both the project and Syngene. The candidate should be capable of independently solving chemistry problems. He or she should ensure that the experimental observations are recorded contemporaneously and in compliance with the Electronic Laboratory Notebook (ELN) policies of the project and Syngene. Role Accountabilities: Perform synthetic chemistry reactions, reaction workups, purification of the compounds by column chromatography, crystallization, re-crystallization techniques, preparative TLC and operating lab equipment's. Ensure that the samples generated during synthesis are given for analysis and record subsequent results obtained and update the supervisor / group leader on the progress of synthesis and ensure samples are packed appropriately for shipment. Record the observations of experiment/reaction, results, utilization of resources and other activities related to the reaction in the laboratory or e-notebook following guidelines and in timely manner and ensure that the same is handled safely and confidentially. The candidate should be capable of meeting Syngene’s productivity expectations (# of compounds/month and # of steps/month) without compromising on safety and quality. The candidate should be capable of synthesizing the final compounds at a faster turnaround time. The candidate should have excellent analytical interpretation and purification skills. Ensure that they know the SDS of the chemicals they are handling and aware of emergency response procedures in case of accidental spillage, leakage or fire and ensure proper waste segregation as per EHS norms. Always follow EHS and quality system requirements in the workplace ensuring individual safety and lab safety. Attend all mandatory trainings and update training records as and when trainings are completed. Always ensure confidentiality.

Experience in Organic Synthesis / Multi-step Synthesis State-of-the-art scientific knowledge in technical background for synthesis and purification methods Handling reactions from milligram to gram scale Sound knowledge of isolation, separation, and purification techniques Positive and confident individual with strong work ethics Team player with good communication skills Good in English written and spoken (recommendable) Candidates are expected to work for Mithros, with the flexibility to quickly move to work in Taros if required Sr. Chemist Research Associate with MSc. Organic Chemistry (2 to 5 years experience only) Good in English written and spoken (recommendable)

Position: Senior Manager - Peptide Production Grade: G9B / G9A Job Location: Ahmednagar Qualification: M.Sc. (Chemistry) / B.E. (Chemical) / B.Tech (Chemical) Experience: 13-18 yrs experience in Peptide API plant Job Profile 1. To plan and execute peptide manufacturing activities as per the schedule and Budget by optimum utilization of plant capacity 2. To ensure the sustainable quality production with optimum utilization of plant capacity. 3. Monitoring and reduction in process TRT, Cleaning TRT, number of preps per batch on Prep HPLC, Improve yields. Improve the process of Synthesis & Analytical Section. 4. Co-ordinate with Purchase, Planning department to deliver the goods in time. 5. To ensure every day interaction with each department for smooth functioning 6. Compliance of waste water disposal as per IN-HOUSE policy 7. To ensure grooming of disciplined workforce and staff to meet the planned growth charts. 8. Developing different innovative practices to increase productivities and up gradation of work culture. 9. To maintain Good Documentation Practices and Good Laboratory Practices 10. Review of batch process record, Standard Operating procedure and cGMP documents 11. Investigation of Deviation, Change Control & OOS 12. Implementation & follow all safety instruction & practices

Role & responsibilities Incumbent should possess design development know-how of peptide APIs Should have hands on experience in synthesis and purification of peptides and complex generics. Exposure on scale-up, technology transfer and manufacturing of peptide APIs Experience of impurity profiling (process and product related) Must have experience of technical documents preparation and to support regulatory filing Preferred candidate profile M.Tech/M.Sc./Chemical Engineering/Biotechnology degree or equivalent. 15+ years of post-qualification experience in the Peptides field, with a focus on new technologies and PAT (Process Analytical Technology) tools. Experience in operational excellence and Six Sigma methodology will be an added advantage.

Optimize yield, quality, cost Run trials (pH, temp, solvents) Ensure IP/USP quality (HPLC, FTIR) Scale up with consistency Source materials/equipment Update SOPs, train team Cut waste, save resources Ensure regulatory compliance Required Candidate profile Skilled in biopolymer process optimization & scale-up Knowledge of food/pharma quality standards & testing Experienced in HPLC, FTIR, and viscosity testing Knowledge of sustainable manufacturing

Hi, Greetings from Biophore India Pharmaceuticals!! We are hiring for Synthesis R&D /Process R&D/CRO Experience: 3 to 6 Years Qualification: M. Sc ( Organic Chemistry) Walk In date : 19th November 2024, Tuesday . Timings : From 10:00 AM to 02:00 PM . Preferable Male Candidates only If any one not able to attend the interviews , share your CV to " recruitments@biophore.com "

Skills Description Proficiency Level (General Awareness; Working Knowledge; Functional Expert, Mastery ) Functional Skills Organic Chemistry, Purification skills, Inert Reactions, Named Reactions Ability to self-design synthetic schemes, plan and order chemicals and deliver the targets in the stipulated time-line. Excellent trouble-shooting skills Responsible for laboratory maintenance on day to day basis. Functional Expert Behavioral Skills Strong communication skills are essential so as to individually procure chemicals, taking care of laboratory maintenance. Working Knowledge