Specialist - DMPK (Invitro ADME) Aurigene Pharmaceutical Services

10.0 - 15.0 years

10 - 18 Lacs

Bengaluru

Work from Office

Role & responsibilities To perform in vitro ADME assays (solubility, metabolic and plasma stability, CYP inhibition, plasma protein binding studies etc.) Design, conduct and report data from in vitro metabolism studies using various cellular and subcellular systems, e.g., microsomes, hepatocytes, recombinant CYPs/UGTs and transfected cells. Perform assays using automated workstations. To design, program and implement study protocols in automated workstations. Ability to integrate metabolism and other supporting ADME data to predict druggability outcomes. To lead a group of 2-5 members and train juniors for the ongoing assays and technologies. Maintain labs & comply with SHE/regulatory guidelines. Preferred candidate profile Masters with 10+ years of PhD with 2+ years industry experience in Invitro ADME assays.

Posted 6 days ago

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Director, Medicinal Chemistry AVE-Promagne Business Solutions

10.0 - 20.0 years

25 - 35 Lacs

Hyderabad

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You get to collaborate on Medicinal Chemistry of Lead Generation and Lead Optimization of Pipeline Projects. Understand Structure Activity Relationships and Structure Property Relationships of various projects. Collaborate with Medicinal Chemistry, Pharmacology, Analytical, ADME, Tox, IP, Site and Global Leadership. Develop appropriate flow schemes with relevant in vitro, in vivo, ADME/PK and tox studies. Appropriate allocation of resources for maximum cost effectiveness. Work effectively with Project ManagementMake presentations of your projects at various Enveda forums. You work with the site safety head and emphasize the importance of safe practices in the chemistry laboratories Who will thrive in this role Doctor of Philosophy in Synthetic Organic Chemistry15-20 years of post-PhD experience in Medicinal Chemistry Proven track record of delivery of leads and clinical candidates to the pharmaceutical industry. Management and mentoring of synthetic chemists. Good understanding of intellectual property of medicinally valuable compounds with respect to composition of matter, method of use and chemical processes. Strong understanding of safety practices in organic synthesis laboratories. If you don't meet all of the requirements listed here, we still encourage you to apply. No job description is perfect, and we might find an even more suitable opportunity that matches your experience.

Posted 2 weeks ago

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Sr. Executive DMPK Eminence Hr Services Bharuch

5.0 - 10.0 years

6 - 11 Lacs

Vadodara

Work from Office

Bioanalyst who will be responsible for high-quality discovery bioanalysis to support preclinical in vitro ADME and in vivo PK studies. LC-MS/MS based bioanalytical techniques to analyse biological samples in support of Drug Discovery projects. Required Candidate profile Around 5-8 years of experience in discovery bioanalysis to support in vitro ADME and pharmacokinetic studies.

Posted 1 month ago

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