2 Pymol Jobs

Work Schedule Standard (Mon-Fri) Environmental Conditions Adherence to all Good Manufacturing Practices (GMP) Safety Standards Job Title: Scientist II Job Location: India, Bangalore About Company: About The Company Thermo Fisher Scientific Inc. (NYSE: TMO) is the world leader in serving science, with annual revenue of approximately $44 billion. Our Mission is to enable our customers to make the world healthier, cleaner, and safer. Whether our customers are accelerating life sciences research, solving analytical challenges, growing efficiency in their laboratories, improving patient health through diagnostics, or developing and manufacturing life-changing therapies, we are here to support them. Our distributed team delivers an outstanding combination of innovative technologies, purchasing convenience, and pharmaceutical services through our industry-leading brands, including Thermo Scientific, Applied Biosystems, Invitrogen, Fisher Scientific, Unity Lab Services, Patheon, and PPD. Our Innovative Laboratory technologies & Services makes it easier for customers. About Team: Antibody team The antibody team is involved in engineering and development of antibodies, with a deep focus on reagent quality and specificity. The core activities of team include design, development, purification, conjugation and testing of antibodies in a variety of immunoassay applications using pioneering tools and technologies. The goal of the program is advanced product development and creation of product specific information to promote research use. Role & Responsibilities Role: To be an integral part of an antibody development team with a focus on performance and specificity using innovative molecular, protein, and cell biology methods. Responsibilities: Independent experimental planning and execution to meet program goals and schedules. Timely record keeping of results into data sheets and laboratory note-books. Regular mining of literature and keeping oneself up to date with developments in field of antibody development and protein biology. Ideate effectively to recommend improvements in product development and workflows. Compilation and presentation of data in written and oral formats to different audiences including stakeholders and leadership. Active participation in team meetings. Mentoring junior scientists and provide in-lab supervision. Candidate Requirement: Education & Experience levels: Applicants should have Masters with greater than 5 years relevant experience or PhD with greater than 2 years’ experience in a life sciences field with a strong focus on structural biology, protein design, protein purification, molecular biology, immunology, biotechnology or biochemistry. Nature of experience: Extensive experience and knowledge in protein purification and analysis technologies such as affinity or ion exchange chromatography, SEC, HPLC, and SDS-PAGE. Experience and knowledge of protein affinity measurement platforms. Familiar with working in a cell and molecular biology lab, with experience in assays for in vivo of protein expression, protein-protein interaction (using co-immunoprecipitation) or development of immunoassays. Proficiency in display-based antibody development techniques, demonstrating a strong track record of successful projects. Extensive experience and familiarity with antibody or protein engineering, rational design of mutants, and molecular biology. Experience with structural biology and protein modeling and visualization tools such as Pymol, Shrodinger, Discovery Studio or other such programs. Experience with antigen design for immunizations, analysis and identification of epitopic regions desirable. Familiarity or experience in development of conjugation chemistries or performing antibody conjugation. Theoretical or practical experience in antibody development platforms is desirable. Project or work experience in support of relevant skills such as publications, project reports or thesis work. Proficient in MS Office applications such as Word, Powerpoint, Excel and possess a strong statistical knowledge and familiarity with statistical software such as Prism. The successful candidate will be self-motivated and a self-starter who is excellent at learning and applying new concepts for process or product improvements, possess excellent oral and written communication skills to connect to peers and leadership, and will be an excellent teammate with the ability to work with different colleagues. Thermo Fisher Scientific is an equal opportunity employer and value diversity at our company. All qualified applicants will receive consideration for employment without discrimination basis race, color, religion, sex, sexual orientation, gender, gender identity or expression, national origin, protected veteran status, age, genetics, pregnancy, disability or any other legally protected status. Thermo Fisher Scientific aligns with all applicable equal employment opportunity legislation in each jurisdiction in which it operates. We offer competitive remuneration, annual incentive plan bonus, healthcare, and a range of employee benefits. Thermo Fisher Scientific offers employment with an innovative, forward-thinking organization, and outstanding career and development prospects. We offer an exciting company culture that stands for integrity, intensity, involvement, and innovation! ThermoFisher is committed to crafting a diverse work environment that values and respects individuals from all backgrounds. Thermo Fisher Scientific is an EEO/Affirmative Action Employer and does not discriminate on the basis of race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability or any other legally protected status. Show more Show less

Work Schedule Standard (Mon-Fri) Environmental Conditions Laboratory Setting, Office About Team: Antibody team The antibody team is involved in engineering and development of antibodies, with a deep focus on reagent quality and specificity. The core activities of the team include design, development, purification, conjugation, and testing of antibodies in a variety of immunoassay applications using groundbreaking tools and technologies. The goal of the program is advanced product development and creation of product-specific information to promote research use. Role: To be an integral part of an antibody development team with a focus on performance and specificity using innovative molecular, protein, biochemical, and cell biology methods. Responsibilities: Meticulous experimental planning and execution to meet program goals. Timely record keeping of results into data sheets and laboratory notebooks. Regular mining of literature and keeping oneself up to date with developments in the field. Compilation and presentation of data in written and oral formats. Active participation in team meetings with attention to detail and adherence to schedules. Strong theoretical and proven understanding of protein and antibody conjugation chemistries. Hands-on experience in performing protein or antibody conjugations to dyes, labels, or reporter tags. Experience with the development of new conjugation protocols and the design of site-specific conjugation strategies is desirable. Experience and knowledge in protein purification and analysis technologies such as affinity or ion exchange chromatography, SEC, HPLC, and SDS-PAGE. Experience or familiarity with antibody or protein engineering, rational design of mutants, and molecular biology. Experience with structural biology and protein modeling and visualization tools such as Pymol, Shrodinger, Discovery Studio or other similar programs is desirable. Theoretical or practical experience in antibody development platforms is desirable. Proficient in MS Office applications such as Word, PowerPoint, Excel, and possess a strong statistical knowledge and familiarity with statistical software such as Prism. Seeking self-motivated candidate who excels in learning and applying new concepts for process or product improvements. Must have strong interpersonal skills to connect with peers and leadership. Show more Show less