Senior Research Scientist DMPK Krish Biotech Research

2.0 - 6.0 years

0 Lacs

kolkata, west bengal

On-site

You will be responsible for providing drug metabolism and pharmacokinetic support for discovery programs. Your main duties will include monitoring Pharmacokinetics studies, supporting bioanalysis, and offering pre-clinical ADME lead optimization support to small molecule Drug Discovery programs across various therapeutic areas. You will be working as a DMPK subject matter lead in multidisciplinary/cross-functional teams to understand the Chemical Structure ADME relationships and design appropriate strategies to enhance the Drug like Properties of the New Chemical Entities. To be successful in this role, you should have 2-5 years of experience in GLP with either an M.Sc. or Ph.D. degree. You should possess expertise in Bioanalysis using LC-MS/MS in both GLP and non-GLP environments. Additionally, you should be capable of leading projects as a DMPK representative, quantifying small molecules using LC-MS/MS, and conducting metabolite identification work on High-resolution mass spectrometry. Qualifications required for this position include an M. Pharm (Pharmacology / Pharmaceutical Analysis) or an M.Sc. (Biochemistry / Pharmaceutical Chemistry).,

Posted 2 days ago

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Associate Software Engineer - Large Molecule Discovery Amgen Inc

1.0 - 3.0 years

3 - 5 Lacs

Hyderabad

Hybrid

What you will do The role is responsible for designing, developing, and maintaining software solutions for Research scientists. Additionally, it involves automating operations, monitoring system health, and responding to incidents to minimize downtime. You will join a multi-functional team of scientists and software professionals that enables technology and data capabilities to evaluate drug candidates and assess their abilities to affect the biology of drug targets. This team implements scientific software platforms that enable the capture, analysis, storage, and reporting for our Large Molecule Discovery Research team (Design, Make, Test and Analyze processes). The team also interfaces heavily with teams supporting our in vitro assay management systems and our compound inventory platforms. The ideal candidate possesses experience in the pharmaceutical or biotech industry, strong technical skills, and full stack software engineering experience (spanning SQL, back-end, front-end web technologies, automated testing). Roles & Responsibilities: Work closely with product team, business team including scientists, and other stakeholders Analyze and understand the functional and technical requirements of applications, solutions and systems and translate them into software architecture and design specifications Design, develop, and implement applications and modules, including custom reports, interfaces, and enhancements Develop and execute unit tests, integration tests, and other testing strategies to ensure the quality of the software Conduct code reviews to ensure code quality and adherence to best practices Create and maintain documentation on software architecture, design, deployment, disaster recovery, and operations Provide ongoing support and maintenance for applications, ensuring that they operate smoothly and efficiently Stay updated with the latest technology and security trends and advancements. What we expect of you We are all different, yet we all use our unique contributions to serve patients. Basic Qualifications: Masters degree OR Bachelors degree with 1 - 3 years of experience in Computer Science, IT, Computational Chemistry, Computational Biology/Bioinformatics or related field OR Diploma with 4 - 6 years of experience in Computer Science, IT, Computational Chemistry, Computational Biology/Bioinformatics or related field Preferred Qualifications: 1+ years of experience in implementing and supporting biopharma scientific software platforms Must-Have Skills: Experience in Java or Python Experience in at least one JavaScript UI Framework (e.g. ExtJS, React, or Angular) Experience in SQL (e.g. Oracle, PostgreSQL, Databricks) Good-to-Have Skills: Experience with event-based architecture and serverless AWS services such as EventBridge, SQS, Lambda or ECS. Experience with Benchling Hands-on experience with Full Stack software development Strong understanding of software development methodologies, mainly Agile and Scrum Working experience with DevOps practices and CI/CD pipelines Experience of infrastructure as code (IaC) tools (Terraform, CloudFormation) Experience with monitoring and logging tools (e.g., Prometheus, Grafana, Splunk) Experience with automated testing tools and frameworks Experience with big data technologies (e.g., Spark, Databricks, Kafka) Experience with leveraging the use of AI-assistants (e.g. GitHub Copilot) to accelerate software development and improve code quality Professional Certifications AWS Certified Cloud Practitioner preferred Soft Skills: Excellent problem solving, analytical, and troubleshooting skills Strong communication and interpersonal skills Ability to work effectively with global, virtual teams High degree of initiative and self-motivation Ability to learn quickly & work independently Team-oriented, with a focus on achieving team goals Ability to manage multiple priorities successfully Strong presentation and public speaking skills

Posted 1 month ago

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